Table 1.
Demographic, Laboratory, and Atherosclerosis Variables in the Sample Population
| Variables | Overall (n = 204) | Male (n = 134) | Female (n = 70) |
|---|---|---|---|
| Demographic | |||
| Age, y (mean ± SD) | 65.5 ± 9.4 | 65.8 ± 9.8 | 65.0 ± 8.7 |
| Diabetes, n (%) | 63 (31) | 38 (28) | 25 (36) |
| Hypertension, n (%) | 154 (75) | 96 (72) | 58 (83) |
| Dyslipidemia, n (%) | 168 (82) | 110 (82) | 58 (83) |
| Tobacco use, n (%) | 32 (16) | 19 (14) | 13 (19) |
| BMI, (mean ± SD) | 30.1 ± 6.7 | 29.7 ± 6.1 | 30.8 ± 7.6 |
| BMI ≥30, n (%) | 79 (39) | 51 (38) | 28 (40) |
| WC, cm (mean ± SD) | 106.6 ± 14.1 | 107.9 ± 13.1 | 103.9 ± 15.9 |
| Laboratory variables | |||
| Creatinine, μmol/L (mean ± SD) | 85.1 ± 27.2 | 91.8 ± 28.6 | 72.4 ± 18.5a |
| eGFR, mL/min/m2 (mean ± SD) | 77.4 ± 21.8 | 78.5 ± 22.4 | 75.2 ± 20.5 |
| FGF-23, RU/m, median (IQR) | 69.1 (45.0–113.8) | 61.7 (43.4–95.7) | 90.9 (54.1–168.7)a |
| Phosphate, mmol/L (mean ± SD) | 1.13 ± 0.27 | 1.13 ± 0.27 | 1.13 ± 0.26 |
| Angiographic score (mean ± SD) | 2.1 ± 1.2 | 2.3 ± 1.2 | 1.8 ± 1.2b |
| 0 (normal, no CAD), n (%) | 32 (16) | 20 (15) | 12 (17) |
| 1 (mild CAD), n (%) | 38 (19) | 15 (11) | 23 (33) |
| 2 (moderate CAD), n (%) | 9 (4) | 5 (4) | 4 (6) |
| 3 (severe CAD), n (%) | 125 (61) | 94 (70) | 31 (44) |
| Carotid ultrasound measures (mean ± SD) | |||
| Mean CIMT, mm | 0.81 ± 0.15 | 0.82 ± 0.16 | 0.79 ± 0.14 |
| Maximum plaque height, mm | 2.97 ± 1.35 | 3.01 ± 1.33 | 2.88 ± 1.39 |
| Total plaque area, mm2 | 55.7 ± 40.6 | 59.4 ± 43.0 | 48.5 ± 34.8 |
| Mean GSM | 58.3 ± 13.6 | 58.1 ± 13.3 | 58.9 ± 14.2 |
Abbreviations: CAD, coronary artery disease; WC, waist circumference.
Two-tailed Fisher exact test was used to compare nominal variables, and the Wilcoxon test (rank sums) was used for continuous variables.
a
P < 0.0001.
b
P < 0.01.