Table 1.
Clinicopathological features in the three groups
| Clinical characteristics | Group A (n = 1858) | Group B (n = 31) | Group C (n = 18) | p value | |
|---|---|---|---|---|---|
| A vs. B | B vs. C | ||||
| Sex (M:F) | 1421:437 | 25: 6 | 11:7 | 0.741 | 0.102 |
| Age (years) | 63 (18–84) | 86 (85–95) | 87 (85–92) | < 0.001 | 0.914 |
| Serum hepatitis states | 0.024 | 0.894 | |||
| B + C+ | 108 (5.8%) | 1 (3.2%) | 0 | ||
| B + C− | 873 (47.0%) | 11 (35.5%) | 5 (27.8%) | ||
| B − C+ | 590 (31.8%) | 13 (41.9%) | 10 (55.6%) | ||
| B − C− | 287 (15.4%) | 6 (19.4%) | 3 (16.7%) | ||
| Serum AFP (ng/ml) | 30.9 (0.63–3,395,610) | 28.3 (1.29–15,321) | 34.6 (12.0–127,911) | 0.814 | 0.758 |
| ICG 15 (%) | 13.5 (1.38–59.65) | 15.3 (6.60–29.53) | 14.2 (5.4–38.0) | 0.814 | 0.758 |
| Child-Pugh grade | |||||
| A:B:C | 1612:205:41 | 27:3:1 | 16:2:0 | ||
| Need for splenectomy | 141 (7.5%) | 1 (3.2%) | 1 (5.3%) | 0.190 | 0.711 |
| Associated with EGV | 800 (16.0%) | 4 (12.9%) | 2 (11.1%) | 0.584 | 0.899 |
| Associated with comorbidities | 454 (24.3%) | 29 (93.8%) | 16 (88.9%) | < 0.001 | 0.916 |
| Cardiopulmonary | 201 | 20 | 12 | ||
| Neurologic | 10 | 2 | 0 | ||
| Hepatico-gastroenterologic | 66 | 4 | 0 | ||
| Endocrine and metabolic | 125 | 6 | 6 | ||
| Genitoenphrologic | 69 | 3 | 1 | ||
| Hematologic | 72 | 0 | 0 | ||
| Rheumatologic | 19 | 3 | 0 | ||
| Others | 41 | 2 | 2 | ||
Hepatitis states: B + C+, positive for HBsAg and anti-HCV; B + C−, positive for HBsAg, negative for anti-HCV; B− C+, negative for HBsAg and positive for anti-HCV; B− C−, negative for HBsAg and anti-HCV; AFP α-fetoprotein, ICG 15 indocyanine-green 15-min retention test, EGV esophagogastric varice