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. 2019 Jan 3;7:1. doi: 10.1186/s40478-018-0656-4

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Imaging studies. a, d: DWI images show diffuse signal abnormalities involving bilaterally the posterior temporal cortex, caudate and putamen, parietal and frontal cortex, more marked in the right side (Case 1). b, e: Axial Flair and coronal T2-weighted images show diffuse cortical atrophy, involving frontal lobe with mild left prevalence (Case 2). c, f: DWI images show marked signal abnormalities in frontal and parietal right cortex and in right cingulus (Case 3)