Table 3.
Agreement between phenotypic and genotypic test results
| Genotypic result | Phenotypic result (N) | Cohen’s Kappa (95% confidence interval) | |
|---|---|---|---|
| Resistant | Susceptible | ||
| INH | |||
| Mutated (N = 12) | 12 | 0 | 0.824 (0.632–1.000) |
| Unmutated (N = 24) | 3 | 21 | |
| RFP | |||
| Mutated (N = 11) | 11 | 0 | 1.000 (1.000–1.000) |
| Unmutated (N = 25) | 0 | 25 | |
| EMB | |||
| Mutated (N = 8) | 7 | 1 | 0.916 (0.753–1.000) |
| Unmutated (N = 28) | 0 | 28 | |
| PZA | |||
| Mutated (N = 4) | 4 | 0 | 0.609 (0.247–0.970) |
| Unmutated (N = 4) | 4 | 28 | |
| SM | |||
| Mutated (N = 4) | 4 | 0 | 0.491 (0.118–0.683) |
| Unmutated (N = 32) | 6 | 26 | |
| AMK, KM | |||
| Mutated (N = 0) | 0 | 0 | N/A |
| Unmutated (N = 36) | 2 | 34 | |
| FQ | |||
| Mutated (N = 4) | 4 | 0 | 0.769 (0.458–1.000) |
| Unmutated (N = 32) | 2 | 30 | |
INH isoniazid, RFP rifampin, EMB ethambutol, PZA pyrazinamide, SM streptomycin, AMK amikacin, KM kanamycin, FQ fluoroquinolones