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. 2018 Dec 29;15:e00479. doi: 10.1016/j.idcr.2018.e00479

Table 2.

This table summarize all adult cases of neuroborreliosis related transverse myelitis reported in English literature. It includes patients’ demographics, country of origin, most common symptoms and signs as well as treatment and outcome of the diseases.

Case
(Ref)
Year Age
(y/o)
Sex Country Systemic
illnesses
Time between symptom onset and diagnosis Diagnostics Oligoclonal bands Erythema migrans Autonomic dysfunction Sensory level Images Therapy Outcome
1
([8])
1986 19 F Belgium none 2 weeks CSF WBC-10, 90% lymphocytes;
+ Serum antibodies (IgG)
Positive Yes None T4 No Penicillin G for 2 weeks Improved
2
([9])
1995 42 M UK none 5 days LP not done (patient declined)
Serum antibodies positive (not specified IgM or IgG)
N/A Yes None C5-6 MRI Cefotaxime 6 g/day for 1 week then 8 weeks of doxycycline Improved
3
([10])
2002 40 M France none 1 week CSF WBC-205, 90% lymphocytes.
CSF antibodies IgM and IgG positive
Yes Yes Urinary and bowel incontinence C2 MRI Ceftriaxone 2 g/day for 3 weeks. Improved
4
([11])
2005 50 M France none 4 weeks CSF WBC-16, 100% lymphocytes; Intrathecal B.burgdorferi Ab production +
Serum and CSF PCR+
Yes No None Not reported MRI Ceftriaxone 4 weeks, doxycycline 4 weeks and IV steroids Improved
5
([12])
2008 46 F Georgia, USA none 3 weeks Positive antibodies in blood (IgM and IgG) Negative No Urinary retention, constipation T6 MRI Ceftriaxone for 1 week plus doxycycline for 3 weeks
plus IV Methylprednisolone
Improved
6
([13])
2009 21 F Turkey none 3 months CSF WBC-20, 86% lymphocytes.
CSF and serum antibodies + (IgM and IgG)
Negative No None T11 MRI Ceftriaxone 4 g/day for 28 days plus (200 mg/day of doxycycline Improved
7
Our case
2018 25 M Wisconsin, USA none 2 weeks CSF WBC 316, 76% lymphocytes,
+ CSF B.burgdorferi PCR
Negative Yes Urinary retention,
constipation
T5 MRI IV ceftriaxone (28 days) and IV Methylprednisolone (3 days) Improved