Figure 1.
In vivo whole-cell recording of CSD. In vivo current clamp recording showing membrane voltage prior to, during, and for 40 min after CSD, induced by focal 1 M KCl ejection >2 mm from recording electrode (induction marked with arrow). Spontaneous synaptic potentials and APs are evident prior to CSD, are completely abolished during and immediately after the depolarization, and return but remain significantly reduced for the duration of the recording. Gaps in recording are during induced hyperpolarization and depolarization current steps to record evoked firing.