Table 1.
Top 10 manually validated genes with evidence for marine-specific loss
| Gene | Loss rate (independent) | Marine loss rate (dependent) | Terrestrial loss rate (dependent) | LRT statistic | Empirical P-value | FDR | Description |
|---|---|---|---|---|---|---|---|
| PON1 | 0.672 | 49.7 | 0 | 22.24 | 3.08 × 10−6 | 0.0154 | paraoxonase 1 |
| ORIOZI | 1.15 | 100 | 0.467 | 19.99 | 7.25 × 10−6 | 0.0201 | olfactory receptor |
| OR8D4 | 1.25 | 100 | 0.510 | 19.21 | 1.60 × 10−5 | 0.0201 | olfactory receptor |
| TAS2R1 | 1.32 | 100 | 0.535 | 19.20 | 1.60 × 10−5 | 0.0201 | taste receptor |
| OR1F2P | 2.03 | 100 | 1.18 | 15.86 | 5.40 × 10−5 | 0.0831 | olfactory receptor |
| GSTM1 | 1.48 | 100 | 0.762 | 15.82 | 3.90 × 10−5 | 0.0831 | glutathione S-transferase mu 1 |
| OR6K2 | 2.02 | 100 | 1.22 | 15.79 | 4.50 × 10−5 | 0.0831 | olfactory receptor |
| OR51D1 | 1.13 | 49.3 | 0.466 | 15.59 | 8.60 × 10−5 | 0.0831 | olfactory receptor |
| TAAR5 | 1.17 | 48.2 | 0.484 | 15.16 | 9.90 × 10−5 | 0.0936 | trace amine associated receptor 5 |
| OR4C13 | 1.77 | 100 | 0.915 | 14.88 | 7.00 × 10−5 | 0.0972 | olfactory receptor |