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. 2018 Sep 9;167(1):172–189. doi: 10.1093/toxsci/kfy231

Figure 2.

Figure 2.

Coordinate activation of CAR and Nrf2 by PB across studies. A, (Top) Significance of the correlation between biomarkers for CAR or Nrf2 and 25 biosets from the livers of WT mice treated with PB from 12 studies (GSE16777; GSE34423; GSE40120; GSE40773; GSE43977; GSE44783; GSE45465; GSE51355; GSE55084; GSE57055; GSE60684; GSE6721). Biosets were rank ordered by the significance of the similarity of the biosets to the CAR biomarker. (Bottom) Expression of the genes in the biomarkers across the studies. B, Relationships between the −log(p-value)s of the correlations described in (A).