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Electrostatic surfaces. Top: the endothelin dimer in the same orientation as in Fig. 1 ▸ presented as an electrostatic surface. Center: the molecule rotated by 90°. Bottom: the molecule rotated by a full 180°. It is evident that the molecule is extremely hydrophobic in character, with a paucity of exposed charged groups. C atoms are white, O atoms red and N atoms blue.
