Table 1.
Representative clinical studies using LSCs or their alternatives to treat LSCD.
| Procedures | Year | Authors | Type of graft |
Number of patients | Success rate | Improved visual acuity | Follow up month Mean/Median [range] |
Reference |
|---|---|---|---|---|---|---|---|---|
| CLAU | 1989 | Kenyon et al. | Autograft | 21 | 95% | 81% | Median 24 [6–45] |
[30] |
| KLAL | 2003 | Holland et al. | Allograft | 31 | 74.2% | 87.1% | Mean 35.7 [12–117] |
[62] |
| CLET (3T3-J2, fibrin) | 2010 | Rama et al. | Autograft | 107 | 68.2% | 56.1% | Mean 35 [12–120] |
[64] |
| CLET (xeno-free, HAM) | 2011 | Sangwan et al. | Autograft | 200 | 71% | 60.5% | Mean 36 [12–91] |
[65] |
| SLET | 2016 | Basu et al. | Autograft | 125 | 76% | 75.2% | Median 18 [12–48] |
[68] |
| COMET | 2011 | Satake et al. | Autograft | 40 | 57.5% | 59% | Mean 25.5 [6–54.9] |
[71] |
| EVCAU | 2013 | Ricardo et al. | Autograft | 12 | 83.3% | 75% | Mean 18.5 [15–26] |
[43] |