TABLE 5.
Univariable Analysis of Patient, Provider, and Practice Characteristics and Adverse Events During Intubations Performed in the NICU
| Factor | TIAEs | Severe Desaturations | ||||
|---|---|---|---|---|---|---|
| Any TIAE (n = 361) | No TIAE (n = 1648) | P | Severe Desaturation (n = 938) | No Severe Desaturation (n = 1012) | P | |
| Patient current wt, g, median (IQR) | 1300 (782–2595) | 1940 (1000–3100) | <.001 | 1600 (900–3000) | 1925 (1034–3050) | .01 |
| Gestational age at birth, wk, median (IQR) | 27 (25–32) | 29 (25–35) | <.001 | 28 (25–34) | 30 (26–36) | <.001 |
| Patient postnatal age, d, median (IQR) | 13 (1–42) | 13 (1–50) | .35 | 20 (2–56) | 6 (1–44) | <.001 |
| Indication, n (%) | ||||||
| Ventilation failure | 134 (37) | 625 (38) | .78 | 358 (38) | 390 (39) | .87 |
| Oxygen failure | 114 (32) | 515 (31) | .90 | 307 (33) | 311 (31) | .34 |
| Frequent apnea and bradycardia events | 95 (26) | 302 (18) | .001 | 206 (22) | 176 (17) | .01 |
| Surfactant administration | 70 (19) | 293 (18) | .47 | 142 (15) | 209 (21) | .002 |
| Reintubation after unplanned extubation | 48 (13) | 204 (12) | .63 | 129 (14) | 115 (11) | .11 |
| Upper airway obstruction | 26 (7) | 84 (5) | .11 | 59 (6) | 48 (5) | .13 |
| Procedure | 17 (5) | 197 (12) | <.001 | 87 (9) | 120 (12) | .06 |
| Unstable hemodynamics | 14 (4) | 26 (2) | .005 | 19 (2) | 18 (2) | .69 |
| First providera | ||||||
| Pediatric resident | 60 of 187 (32%) | 239 of 861 (28%) | .47 | 169 of 509 (33%) | 126 of 513 (25%) | .003 |
| NICU fellow | 102 of 187 (55%) | 507 of 861 (59%) | 269 of 509 (53%) | 323 of 513 (63%) | ||
| NICU attending | 25 of 187 (13%) | 115 of 861 (13%) | 71 of 509 (14%) | 64 of 513 (12%) | ||
| Video laryngoscopeb | 26 of 192 (14%) | 387 of 990 (39%) | <.001 | 192 of 573 (34%) | 214 of 593 (36%) | .36 |
| Sedative premedication | 198 (55%) | 1086 (66%) | <.001 | 634 (68%) | 632 (62%) | .02 |
| Paralytic premedicationc | 95 of 341 (28%) | 850 of 1589 (53%) | <.001 | 430 of 904 (48%) | 503 of 969 (52%) | .06 |
| No. attempts, median (IQR) | 3 (2–4) | 1 (1–2) | <.001 | 2 (1–3) | 1 (1–2) | <.001 |
IQR, interquartile range.
a
First provider analysis only includes intubations with resident, fellow, or attending providers.
b
Video laryngoscope analysis only includes sites that report any video laryngoscope use.
c
Analysis of paralytic medication only includes sites that reported any paralytic use.