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. 2018 Nov 30;74(Pt 12):1169–1177. doi: 10.1107/S2059798318004771

Table 1. X-ray diffraction data for lipid-raft mixtures in the presence of halogenated anesthetics.

%Δ1H indicates the percentage change in the ratio of first-order diffraction peaks Lo/Ld upon adding anesthetic. %MAC indicates the concentration used as a percentage of the minimum alveolar concentration necessary for humans. At least two experiments on separate samples were performed for each anesthetic. Mean values are tabulated with standard errors. Reprinted with permission from Weinrich & Worcester (2013). Copyright 2013 American Chemical Society.

Mixture Anesthetic %Δ1H %MAC
DOPC:DPPC/cholesterol 1:1/0.2      
  Halothane 31 ± 3 270 ± 60
  Isoflurane 17 ± 2 121 ± 22
  Chloroform 22 ± 2 167 ± 17
DOPC:SPM/cholesterol 1:1/0.2      
  Halothane 21 ± 5 540 ± 20
  Isoflurane 20 ± 3 300 ± 60
  Chloroform 25 ± 8 262 ± 26