Table 6.

Correlations of changes in neuroimaging with change in cognitive testing over 12 months, in those who remain on hemodialysis and those receiving a kidney transplant

Assessment	Correlation with ΔWMH	P Value	Correlation with ΔFA_WM	P Value
Continued hemodialysis, n=21
MOCA	0.172	0.46	0.225	0.48
Semantic	−0.028	0.90	−0.175	0.59
Phonemic	0.585	0.01	−0.365	0.24
LDST	0.129	0.58	0.116	0.72
TMTA	0.328	0.16	−0.278	0.41
TMTB	−0.384	0.12	−0.103	0.78
HVLT
Total recall	0.271	0.23	0.327	0.30
Delayed recall	0.268	0.24	0.160	0.62
Retention	0.172	0.46	0.056	0.86
Discrimination	0.296	0.19	−0.381	0.22
CES-D	−0.485	0.03	0.140	0.66
Transplanted at follow-up, n=9
MOCA	−0.092	0.81	0.319	0.54
Semantic	−0.301	0.43	−0.600	0.21
Phonemic	0.460	0.21	−0.667	0.15
LDST	−0.101	0.80	−0.886	0.02
TMTA	0.071	0.87	0.200	0.75
TMTB	−0.810	0.02	−0.600	0.29
HVLT
Total recall	0.025	0.95	−0.232	0.66
Delayed recall	0.522	0.15	0.353	0.49
Retention	0.483	0.19	−0.143	0.79
Discrimination	−0.173	0.65	0.152	0.77
CES-D	0.460	0.21	−0.143	0.79

For all neuroimaging results, values show follow-up minus baseline, hence a reduction in value with time will produce a negative result. Difference in cognitive score is calculated as baseline minus follow-up score. Therefore, a positive rho indicates that a positive neuroimaging change relates to a positive cognitive score at follow-up. In the above tests, a positive follow-up cognitive score denotes deterioration, with the exception of TMTA, TMTB, and CES-D, where the inverse is true. FA_WM, Fractional anisotropy in white matter; CES-D, Center for Epidemiologic Studies Depression Scale.