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. 2018 Nov 26;43(2):709–716. doi: 10.3892/ijmm.2018.3999

Figure 4.

Figure 4

Effects of AST on transcriptional factors, snail, slug, twist and ZEB-1. (A) Western blot analysis of snail, slug, twist and ZEB-1. Relative abundance of (B) snail, (C) slug, (D) twist and (E) ZEB-1. Data are expressed as mean ± standard error. n=3. **P<0.01 vs. NG group; #P<0.05 vs. HG group; ##P<0.01 vs. HG group. AST, astragaloside IV; NG, normal glucose 5.56 mmol/l; MA, normal glucose 5.56 mmol/l + mannitol 54.44 mmol/l; HG, high glucose 60 mmol/l; Rap, high glucose + 20 nmol/l rapamycin; ASTL, high glucose + 50 µg/ml AST; ASTM, high glucose + 100 µg/ml AST; ASTH, high glucose + 200 µg/ml AST; ZEB-1, zinc finger E-box-binding homeobox 1.