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. 2018 Nov 26;43(2):868–878. doi: 10.3892/ijmm.2018.3998

Figure 3.

Figure 3

Expression of FKBP52, AR, ERK1/2 and p-ERK1/2 in rats. (A) Comparison of mRNA expression levels of FKBP52 and AR among the three groups (mean ± SD, n=8 per group). The mRNA expression levels of FKBP52 and AR in the rat ovarian tissues of the PM group were significantly higher than those in the NC and OC groups. No significant difference was found between the NC and OC groups (P>0.05). (B) Comparison of protein expression levels of FKBP52, AR, ERK1/2 and p-ERK1/2 among the three groups (mean ± SD, n=8 per group). The protein expression levels of FKBP52, AR and p-ERK1/2 in the rat ovarian tissues of the PM group were significantly higher than those in the NC and OC groups. No significant difference was found between the NC and OC groups. Protein expression of ERK1/2 did not differ significantly among the groups. Experiments were performed in triplicate and repeated three times. *P<0.05, **P<0.01 and ***P<0.001 NC group vs. PM group; #P<0.05, ##P<0.01 and ###P<0.001 OC group vs. PM group. FKBP52, FK-506 binding protein 52; AR, androgen receptor; ERK1/2, extracellular signal-regulated kinase; p-ERK1/2, phosphorylated ERK1/2; PM, polycystic ovarian syndrome model; NC, normal control; OC, oil control; SD, standard deviation.