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. 2018 Nov 23;54(2):627–643. doi: 10.3892/ijo.2018.4645

Figure 8.

Figure 8

Energy delivery can be well focused, but the heat and the temperature spread. This initiates competitive processes: whether the thermal cell killing, or the tumor-supporting effects are stronger. The control is indefinite. The main risk is compounded by increased tumor cell dissemination, leading to distant micro- and macrometastases.