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. 2018 Dec 18;43(2):807–820. doi: 10.3892/ijmm.2018.4035

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Copyright: © Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Evaluation of locomotor function in different groups. (A) BBB score evaluation was performed at 7, 14, 21 and 28 dpo, in the Sham, Model, and EA Model rats. ^*P<0.05 vs. Model; ^{^}P<0.05 vs. Sham. (B) BBB score evaluation in the EA Model injected with artificially synthetic HSV-IGF-1, HSV-siRNA-IGF-1, HSV-pNX-CMV or HSV-pNX-U6 into the spared L5 DRG. ^#P<0.05 vs. HSV-pNX-CMV; ^&P<0.05 vs. HSV-pNX-U6. Values are plotted as the mean ± standard deviation (n=7). Sham, sham-operated; Model, bilateral dorsal root ganglionectomy injury; EA, electro-acupuncture treatment post-injury; BBB, Basso, Beattie, Bresnahan; IGF-1, insulin-like growth factor 1; siRNA, small interfering RNA.