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. 2018 Dec 18;43(2):791–806. doi: 10.3892/ijmm.2018.4030

Table V.

Genes with inverted expressions between Mo and MOMa group

A, Genes with upregulated expression in the MO group but downregulated expression in the MOMa group
Gene symbol Description Gene ID Fold MO Fold MOMA
Glra1 Glycine receptor, α1 25674 2.10 0.65
Olr1595 Olfactory receptor 1595 304990 1.70 0.66
Ndufaf1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 296086 1.42 0.72
RGD1563091 Similar to OEF2 500011 1.40 0.79
Gnb1 Guanine nucleotide binding protein (G protein), βpolypeptide 1 24400 1.40 0.76
Ccdc122 Coiled-coil domain containing 122 100360752 1.39 0.61
Csta Cystatin A (stefin A) 288067 1.35 0.70
Blvra Biliverdin reductase A 116599 1.33 0.70
MGC114464 Similar to expressed sequence AI836003 500925 1.32 0.75
LOC100910655 Paralemmin-2-like 100910655 1.31 0.64
Dync1i1 Dynein cytoplasmic 1 intermediate chain 1 29564 1.31 0.79
LOC685007 Similar to unc-93 homolog A 685007 1.30 0.68
Cckbr Cholecystokinin B receptor 25706 1.29 0.78
Art4 ADP-ribosyltransferase 4 312806 1.29 0.72
Zbtb41 Cytochrome C oxidase assembly factor 5 503252 1.28 0.75
Cnga4 Cyclic nucleotide gated channel α4 85258 1.28 0.78
Thg1l tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 303067 1.26 0.82
Mettl11b Methyltransferase like 11B 289167 1.25 0.68
LOC100911235 Mediator of RNA polymerase II transcription subunit 7-like 100911235 1.25 0.81
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 24473 1.24 0.75
Pou3f2 POU class 3 homeobox 2 29588 1.24 0.77
B, Genes with downregulated expression in the MO group but upregulated expression in the MOMa group
Gene symbol Description Gene ID Fold MO Fold MOMA
Itpr3 Inositol 1,4,5-trisphosphate receptor, type 3 25679 0.59 1.82
Mocs1 Molybdenum cofactor synthesis 1 301221 0.69 1.66
Col5a3 Collagen, type V, α3 60379 0.73 1.66
Mrc1 Mannose receptor, C type 1 291327 0.66 1.65
Lims2 LIM and senescent cell antigen like domains 2 361303 0.65 1.63
Gtf2a1l General transcription factor IIA, 1-like 316711 0.76 1.58
Olr1147 Olfactory receptor 1147 300408 0.60 1.55
Ccnt2 Cyclin T2 304758 0.82 1.51
Map3k6 Mitogen-activated protein kinase kinase kinase 6 313022 0.64 1.45
Tnfrsf25 Tumor necrosis factor receptor superfamily, member 25 500592 0.71 1.43
Slc41a1 Solute carrier family 41, member 1 363985 0.83 1.43
Mvb12b Multivesicular body subunit 12B 362118 0.80 1.42
Acaca Acetyl-CoA carboxylase α 60581 0.77 1.38
Ryr3 Ryanodine receptor 3 170546 0.77 1.38
Col27a1 Collagen, type XXVII, α1 298101 0.83 1.36
Rasal1 RAS protein activator like 1 (GAP1 like) 360814 0.72 1.36
Rasal1 RAS protein activator like 1 (GAP1 like) 360814 0.72 1.36
Mat2a Methionine adenosyltransferase II 690510 0.79 1.29
er1 Period circadian clock 1 287422 0.63 1.25
Dgkz Diacylglycerol kinase ζ 81821 0.77 1.24

Mo, morphine (morphine infusion/vehicle injection/morphine challenge); MOMa, (morphine infusion/melatonin injection/morphine challenge).