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. 2018 Nov 30;43(2):850–860. doi: 10.3892/ijmm.2018.4007

Figure 12.

Figure 12

TGF-β enhances the effects of miR-27a on caspase-3/9 activity and Bax protein expression of MC3T3-E1 cells. Activity of (A) caspase-3 and (B) caspase-9. (C) Quantified protein expression levels of Bax detected by western blot analysis and (D) representative western blot bands.##P<0.01 vs. control group, **P<0.01 vs. miR-27a mimics group. Groups: Control, negative control group; miR-27a, miR-27a mimics group; TGF-β, miR-27a mimics + TGF-β group. TGF, transforming growth factor; miR, microRNA; B-cell lymphoma-2-associated X protein.