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. 2018 Nov 30;43(2):850–860. doi: 10.3892/ijmm.2018.4007

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Copyright: © Bai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Smad7 enhances the effect of miR-27a on caspase-3/9 activity and Bax protein expression in MC3T3-E1 cells. Activity of (A) caspase-3 and (B) caspase-9. (C) Quantified protein expression levels of Bax detected by western blot analysis and (D) representative western blot bands.^##P<0.01 vs. control group, ^**P<0.01 vs. miR-27a mimics group. Groups: Control, negative control group; miR-27a, miR-27a mimics group; Smad7, miR-27a mimics + Smad7 group. miR, microRNA; Bax, B-cell lymphoma-2-associated X protein.