Figure 4. DVL mRNA expression in GBM, Lung, BRCA and LIHC.
DVL-1, DVL-2 and DVL-3 RNA-seq data were analyzed using TCGA downloaded from Xena tool of UCSC Cancer Genomics Browser (http://xena.ucsc.edu/). Normalized RNA expression is plotted as log2 (norm_count+1). Dysregulated DVL expression between tumor and normal tissue were identified using t-test (p value < 0.001, log2FC > 1 or < −1).