TABLE 3.
Decolonization by Body Area Among 130 Infants Eligible for the mITT-8 and 94 Infants Eligible for the mITT-22
| End Point | Anatomic Sitea | Treatment Group | Primary Decolonization, n (%) | No Primary Decolonization, n (%) | Odds Ratio (95% CI) | P | Efficacy, % |
|---|---|---|---|---|---|---|---|
| Primary decolonization (mITT-8 group) | Nasal | Mupirocin | 62 (95) | 3 (5) | 420 (70–2997) | <.001 | 95 |
| Control | 3 (5) | 61 (95) | — | — | — | ||
| Umbilical | Mupirocin | 27 (100) | 0 (0) | — | <.001 | 100 | |
| Control | 7 (27) | 19 (73) | — | — | — | ||
| Perianal | Mupirocin | 30 (97) | 1 (3) | 98 (9–4270) | <.001 | 96 | |
| Control | 4 (24) | 13 (77) | — | — | — | ||
| Persistent decolonization (mITT-22 group) | Nasal | Mupirocin | 23 (51) | 22 (49) | 49 (7–2066) | <.001 | 50 |
| Control | 1 (2) | 47 (98) | — | — | — | ||
| Umbilical | Mupirocin | 15 (94) | 1 (6) | 56 (5–2518) | <.001 | 92 | |
| Control | 4 (21) | 15 (79) | — | — | — | ||
| Perianal | Mupirocin | 15 (75) | 5 (25) | 12 (2–138) | .007 | 69 | |
| Control | 2 (20) | 8 (80) | — | — | — |
—, not applicable.
a
Each analysis includes only subjects with baseline colonization at the respective anatomic site.