Skip to main content
. 2019 Jan 3;14(1):e0209581. doi: 10.1371/journal.pone.0209581

Table 2. Odds Ratio for overweight/obesity (BMI≥25kg/m2) in 17-year-old offspring associated with cesarean vs. vaginal delivery.

Model 1a Model 2b
OR p-value 95% CI p_interactionc OR p-value 95% CI p_interactionc
Main analyses 1.42 0.001 1.16–1.74 0.013 1.44 0.002 1.14–1.82 0.014
Restricted analysesd 1.43 0.002 1.14–1.78 0.106 1.49 0.002 1.16–1.92 0.086

a Adjusted for maternal education, socioeconomic status, ethnicity and offspring sex

b Further adjusted for proxies for indication for cesarean section (c-section), including toxemia, diabetes in pregnancy, multiple pregnancy, birth order, maternal age at delivery, smoking during pregnancy, preterm and post-term delivery, low and high birth weight and previous c-section

c Interaction was examined by adding cross-product terms between upper quartile of maternal pre-pregnancy BMI (vs. rest) and mode of delivery to the multivariable model

d Subgroup of singleton first births within the cohort, without toxemia or diabetes in pregnancy. The restricted sample included 9,160 offspring born vaginally and 631 born by c-section, of which 1,089 and 102 were overweight/obese, respectively.