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. 2018 Oct 1;142(4):e20181104. doi: 10.1542/peds.2018-1104

TABLE 1.

Demographics, Trimester of Onset of Symptoms (if Any), and Physical Examination Findings in Infants With Normal and Abnormal Eye Examination Results

All Infants (N = 224), n (%) Abnormal Eye Results (N = 57), n (%) Normal Eye Results (N = 167), n (%) P
Born at our institution 91 (40.6) 25 (43.9) 66 (39.5) .64
Female sex 110 (49.1) 30 (52.6) 80 (47.6) .54
Asymptomatic pregnancy 24 (10.7) 13 (22.8) 11 (6.6) <.001
 First trimester symptoms 84 (37.5) 34 (59.6) 50 (29.9)
 Second trimester symptoms 78 (34.8) 9 (15.8) 69 (41.3)
 Third trimester symptoms 38 (17.0) 1 (1.8) 37 (22.2)
Microcephaly, HC <2 SDs 62 (27.7) 43 (75.4) 19 (11.4) <.001
Any CNS abnormality, including microcephaly 90 (40.2) 52 (91.2) 38(22.8) <.001
Normal physical examination findings at birth 134 (60.0) 5 (8.8) 129 (77.2) <.001

HC, head circumference.