. Author manuscript; available in PMC: 2019 Jan 3.

Published in final edited form as: Ann Neurol. 2018 Feb 9;83(2):223–234. doi: 10.1002/ana.25150

TABLE 3.

Correlation between Percentage Change in Thalamic Volume and Percentage Change in Whole Brain Volume

	% Change in Whole Brain Volume over 2 Years	% Change in Whole Brain Volume over 5 Years
% Change in thalamic volume over 1 year	0.35 (0.26–0.44)	0.23 (0.12–0.34)
% Change in thalamic volume over 1 year	p < 0.0001	p < 0.0001
% Change in thalamic volume over 2 years	0.60 (0.52–0.67)	0.40 (0.29–0.51)
% Change in thalamic volume over 2 years	p < 0.0001	p < 0.0001

The association between percentage change in thalamic volume and percentage change in whole brain volume measured with Spearman correlation. Values presented are point estimate (95% confidence interval) and p-value.