Table 2.

Outcomes

Outcome	Arm 1 AUC = 16K	Arm 2 AUC = 20K	P value
Graft failure, n	1	0
Time to engraftment, median (range), days*
Neutrophil	12 (10-21)	12 (10-23)	0.22
Platelet	13 (7-111)	13 (7-70)	0.52
GVHD, cumulative incidence (95% CI)
Acute, grade II-IV	37% (23%-50%)	27% (14%-40%)	0.3
Acute, grade III-IV	2% (0-6%)	13% (3%-22%)	0.05
Chronic	43% (26%-61%)	55% (39%-70%)	0.16
Extensive chronic	31% (17%-44%)	36% (21%-50%)	0.61
1-year relapse, cumulative incidence (95% CI)	34% (20%-49%)	33% (19%-47%)	0.83
Non-relapse mortality, cumulative incidence (95% CI)
Day 100	4% (0-10%)	6.3% (0-13%)	0.65
1 year	20.6% (9%-32%)	22% (10%-34%)	0.69
1-year PFS (95% CI)	48% (36%-65%)	49% (36%-66%)	0.59
1-year OS (95% CI)	59% (46%-74%)	59% (46%-75%)	0.47

^*Among patients with successful engraftment

Abbreviations: AUC, area under the curve; CI, confidence interval; GVHD, graft-versus-host disease; PFS, progression-free survival; OS, overall survival