Table 2.
Summary of Stepwise Regression Analyses for Neuroimaging Predictors of Symptom Severity in Patients with Schizophrenia.
| Positive symptoms |
||||||
|---|---|---|---|---|---|---|
| model | Variable | B (SE B) | β | Adjusted R2 | F | P-value |
| 1 | DMN-SMN | −7.30 (3.33) | −0.23 | 0.04 | 4.80 | 0.03 |
| 2 | DMN-SMN | −10.38 (3.47) | −0.33 | 0.10 | 5.54 | 0.006 |
| DMN-CEN | −6.79 (2.77) | −0.27 | ||||
| 3 | DMN-SMN | −11.29 (3.43) | −0.36 | 0.14 | 5.27 | 0.002 |
| DMN-CEN | −6.06 (2.74) | −0.24 | ||||
| SMN-AN | −7.02 (3.40) | −0.21 | ||||
| Negative symptoms | ||||||
| 1 | SAL-meta | 49.26 (18.88) | 0.27 | 0.07 | 6.80 | 0.01 |
| 2 | SAL-meta | 54.46 (18.23) | 0.30 | 0.14 | 7.61 | 0.001 |
| AN-LAN | 4.70 (1.68) | 0.28 | ||||
| 3 | SAL-meta | 55.84 (17.88) | 0.31 | 0.17 | 6.72 | 0.0004 |
| AN-LAN | 4.83 (1.64) | 0.29 | ||||
| SAL | −23.24 (11.17) | −0.20 | ||||
| Anxiety/depression | ||||||
| 1 | SMN-AN | −6.92 (3.01) | −0.24 | 0.05 | 5.29 | 0.02 |
| 2 | SMN-AN | −7.73 (2.98) | −0.27 | 0.08 | 4.74 | 0.01 |
| SAL | −34.65 (17.31) | −0.21 | ||||
| 3 | SMN-AN | −8.00 (2.92) | −0.28 | 0.12 | 4.76 | 0.004 |
| SAL | −36.42 (16.98) | −0.22 | ||||
| SAL-LAN | −6.06 (2.89) | −0.22 | ||||
| Agitation/disorganization | ||||||
| 1 | SAL-CEN | 6.18 (2.71) | 0.24 | 0.05 | 5.20 | 0.02 |
AN = auditory network; DMN = default mode network; CEN = central executive network; LAN = language network; SAL = salience network; SMN = somatosensory network; Meta = abbreviation for metastability; when the name of a network is used alone it denotes the within-network functional connectivity of that particular network; between-network connectivity is denoted by joining the names of the respective networks with a hyphen.
B: unstandardized B coefficient, SE B: standard-error of the B coefficient.