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. 2018 Dec 13;110(1):289–302. doi: 10.1111/cas.13879

Figure 4.

Figure 4

Upregulation of micro RNA (miR)‐129‐5p inhibits breast cancer cell growth, proliferation and migration, and induces cell apoptosis in vitro. A, qRT‐PCR of miR‐129‐5p in breast cancer cell lines MDA‐MB‐231 and SK‐BR‐3 transfected with lentivirus carrying the miR‐129‐5p sequence or Coi (negative control). B, CCK‐8 assay of MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. C, Colony formation assay of MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. D, Wound healing assay in MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. E, Invasion assay using Transwell assays in MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. F, Flow cytometric evaluation of apoptosis in MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. G, Western blotting of MDA‐MB‐231 and SK‐BR‐3 cells transfected with miR‐129‐5p or Coi lentivirus. **P < .01