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. 2018 Dec 7;110(1):279–288. doi: 10.1111/cas.13876

Figure 4.

Figure 4

Cabazitaxel induced apoptosis through the induction of cleaved caspase‐3 and cleaved PARP. A‐C, The levels of apoptosis‐related proteins, caspase‐3, PARP and Bcl‐xL, in DU145 (A), DU145‐TxR (B) and DU145‐TxR/CxR (C) cells were determined using western blotting. Cells were seeded on 6‐well plates and allowed to attain 60%‐70% confluence, followed by incubation with different concentrations of cabazitaxel