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. 2018 Dec 7;110(1):99–106. doi: 10.1111/cas.13857

Figure 5.

Figure 5

Interactive relationships among microRNA‐223 (miR‐223), circUVRAG, and fibroblast growth factor receptor 2 (FGFR2). A, Predicted binding sites of miR‐223 in circUVRAG. Mutated (Mut) version of circUVRAG is also shown. B, Relative luciferase activity was determined 48 h after transfection with miR‐223 mimic/normal control (NC) or with circUVRAG WT/Mut in HEK293T cells. Data are presented as mean ± SD. ***P < .001. C, Predicted binding sites of miR‐223 with the 3′‐UTR of FGFR2. Mutated version of the 3′‐UTR‐FGFR2 is also shown. D, Relative luciferase activity was determined 48 h after transfection with miR‐223 mimic/NC or with the 3′‐UTR‐FGFR2 WT/Mut in HEK293T cells. Data are presented as mean ± SD. ***P < .001