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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Cell Physiol. 2018 Sep 7;234(4):3910–3920. doi: 10.1002/jcp.27165

Figure1: RvD1 effectively control pro-inflammatory macrophages phenotypes in the absence of 12/15LOX, compared to DHA.

Figure1:

WT and 12/15LOX−/− peritoneal macrophages treated with LA (200μ), 12(S)-HETE (100nM), DHA(50μM) and RvD1(10ng/ml) for 4h and 24 h. mRNA expression of classical M1 markers A. Tnf-α B. IL-6 C. Ccl2 D. IL-1β. Expression levels are normalized to HPRT-1. *p<0.05 vs. untreated cells, $p<0.05 vs. treated WT cells. Results are presented as mean±SEM. Data are representative of a n=3 independent experiments.