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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Cell Physiol. 2018 Aug 25;234(4):4418–4431. doi: 10.1002/jcp.27230

Figure 4. Matrix metalloproteinase 13 (MMP-13), a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-5) expression in knees of 6 month old male Fgf2ALLKO, Fgf2HMWKO, Fgf2LMWKO, and wild-type littermates.

Figure 4.

A, Representative immunohistochemical staining shows increased protein expression of MMP-13 along tibial articular cartilage of Fgf2ALLKO and Fgf2LMWKO (arrows) compared to WT littermates, while Fgf2HMWKO and WT have similar MMP-13 expression. B, Representative images show increased expression of ADAMTS-5 in the enlarged tendon and meniscus area of the medial tibia in both Fgf2ALLKO and Fgf2LMWKO (dashed arrows) compared to WT littermates, whereas Fgf2HMWKO and WT have similar ADAMTS-5 expression of the same area. Magnification=10X, n=3/group.