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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Ann Biomed Eng. 2018 Oct 8;47(1):257–271. doi: 10.1007/s10439-018-02146-4

Table 4.

Area-under-curve (AUC) calculated for the IC50 obtained at four different ranges of time for a simulated tumor spheroid growing in in vitro conditions.

IC50 Range of Time AUC
(μM.h)
24hr IC50 1082
48hr IC50 760
72hr IC50 676
96hr IC50 644