Table 1.
Characteristics of patients with primary testicular DLBCL (2004–2015, N=1,805), stratified by receipt of radiation therapy (RT—note that percentages are given “per row”), and multivariable model for the relative risk (RR) of receiving RT.
| Variable | RT administered |
P a | RR for receiving RT |
||||
|---|---|---|---|---|---|---|---|
| No, N (%) | Yes, N (%) | RR | 95% CI | ||||
| N | 907 | (50.2) | 898 | (49.8) | |||
| Age group | <.001 | ||||||
| 18 to 50 years | 103 | (51.8) | 96 | (48.2) | 0.85 | (0.72–1.00) | |
| 51 to 60 years | 141 | (46.1) | 165 | (53.9) | 0.94 | (0.83–1.06) | |
| 61 to 70 years | 233 | (42.9) | 310 | (57.1) | Reference | ||
| 71 to 80 years | 285 | (51.8) | 265 | (48.2) | 0.86 | (0.76–0.96) | |
| >80 years | 145 | (70.0) | 62 | (30.0) | 0.55 | (0.44–0.68) | |
| Race / ethnicity | .017 | ||||||
| White non-Hispanic | 776 | (49.1) | 806 | (50.9) | Reference | ||
| White Hispanic | 44 | (59.5) | 30 | (40.5) | 0.84 | (0.64–1.11) | |
| Black | 34 | (68.0) | 16 | (32.0) | 0.65 | (0.44–0.97) | |
| Asian or other | 53 | (53.5) | 46 | (46.5) | 0.89 | (0.72–1.10) | |
| Comorbidity index | <.001 | ||||||
| 0 | 688 | (48.0) | 744 | (52.0) | Reference | ||
| ≥1 | 219 | (58.7) | 154 | (41.3) | 0.82 | (0.72–0.93) | |
| Prior malignancy | <.001 | ||||||
| No | 725 | (48.3) | 776 | (51.7) | Reference | ||
| Yes | 182 | (59.9) | 122 | (40.1) | 0.80 | (0.69–0.92) | |
| Health insurance | .08 | ||||||
| Private or Medicare | 850 | (49.7) | 860 | (50.3) | Reference | ||
| Medicaid | 26 | (54.2) | 22 | (45.8) | 1.02 | (0.75–1.39) | |
| Uninsured | 31 | (66.0) | 16 | (34.0) | 0.68 | (0.46–1.02) | |
| Income b | .040 | ||||||
| < $38,000 | 139 | (57.4) | 103 | (42.6) | 0.84 | (0.71–0.99) | |
| $38,000 to $47,999 | 208 | (52.5) | 188 | (47.5) | 0.92 | (0.81–1.04) | |
| $48,000 to $62,999 | 246 | (48.5) | 261 | (51.5) | 0.99 | (0.88–1.10) | |
| ≥ $63,000 | 314 | (47.6) | 346 | (52.4) | Reference | ||
| Ann Arbor stage | <.001 | ||||||
| I | 377 | (42.6) | 508 | (57.4) | Reference | ||
| II | 175 | (54.7) | 145 | (45.3) | 0.79 | (0.69–0.90) | |
| III/IV | 279 | (59.6) | 189 | (40.4) | 0.74 | (0.65–0.83) | |
| Unrecorded | 76 | (57.6) | 56 | (42.4) | 0.76 | (0.62–0.93) | |
| B symptoms | <.001 | ||||||
| Absent or unrecorded | 808 | (49.2) | 835 | (50.8) | Reference | ||
| Present | 99 | (61.1) | 63 | (38.9) | 0.84 | (0.70–1.02) | |
| Distance to facility | .38 | ||||||
| < 20 miles | 674 | (50.9) | 651 | (49.1) | Reference | ||
| ≥ 20 miles | 233 | (48.5) | 247 | (51.5) | 1.06 | (0.96–1.18) | |
| Cancer program | .99 | ||||||
| Community | 614 | (50.2) | 608 | (49.8) | Reference | ||
| Academic/research | 293 | (50.3) | 290 | (49.7) | 0.97 | (0.88–1.07) | |
a
P for univariate comparison using a chi-squared test
b
Median yearly household income in the zipcode of residence according to the 2012 American Community Survey data, grouped by national quartiles.