Table 1.

Definition of Allostatic Load in the Boston Puerto Rican Study (Mattei et al 2010)

Biomarker	Cut-off Points
Neuroendocrine System
DHEA-S (ng/mL) a	Men <= 589.5 or taking medications
	Women <= 368.5 or taking medications
Cortisol: (μg/g creatinine) b	Men >= 41.5
	Women >= 49.5
Norepinephrine: (μg/g creatinine) b	Men >= 30.5
	Women >= 46.9
Epinephrine: (μg/g creatinine) b	Men >= 2.8
	Women >= 3.6
Immune System
C-reactive protein: CRP (mg/L) c	> 3
Cardiovascular system
Systolic Blood Pressure: SBP (mmHg) d	> 140 or taking medications
Diastolic Blood Pressure: DBP (mmHg) d	> 90 or taking medications
Metabolic System
Lipid metabolism
Total Cholesterol: TC (mg/dl) e	>= 240 or taking medications
High Density Lipoprotein: HDL-C (mg/dl) e	< 40 or taking medications
Glucose metabolism
Glycosylated hemoglobin: HbA1c (%) f	> 7 or taking medications
Adipose tissue deposition
Waist Circumference: WC (cm) g	Men > 102
	Women > 88

^aTrivedi and Khaw (2001);

^bGoldman et al (2004);

^cPearson etal (2003);

^dNHLBI (2004);

^eNHLBI (2002);

^fADA (2008);

^gNHLBI (2002)