Fig. 2.

Fabrication of a miRNA sensor integrated with antimonene nanomaterials. Schematic illustration of the strategy employed to detect antimonene-miRNA hybridization events. I The antimonene nanosheets was assembled on the surface of Au film. II AuNR-ssDNAs were adsorbed on the antimonene nanosheets. III miRNA solution with different concentrations flowed through the surface of antimonene, and paired up to form a double-strand with complementary AuNR-ssDNA. IV The interaction between miRNA with AuNR-ssDNA results in release of the AuNR-ssDNA from the antimonene nanosheets. The reduction in the molecular of the AuNR-ssDNA on the SPR surface makes for a significant decrease of the SPR angle