Fig. 1.

The domain architecture and binding property of ADCP1. a Surface plasmon resonance imaging profiling of “Royal family” proteins binding to H3K9me2 peptide. 200 s-500 s was the association phase; 500 s-800 s was the dissociation phase. b The domain architecture of ADCP1. c The ITC fitting curves of H3(1-15)K9me1/2/3 peptides titrated to three tandem Agenet domains of ADCP1. d The ITC fitting curves of histone peptides methylated at different sites titrated to three tandem Agenet domains of ADCP1. e The ITC fitting curves of phosphorylated histone peptides titrated to three tandem Agenet domains of ADCP1