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. 2018 Nov 15;40(1):133–142. doi: 10.1038/s41401-018-0183-7

Fig. 1.

Fig. 1

The plasma and tissue concentrations of BBR and its metabolites in WT and P-gp-KO mice. Concentrations of BBR and its metabolites in the plasma (a) and liver (b) were detected at 2 and 6 h after the oral administration of 150 mg/kg BBR (n = 5/group/time point). Data are mean ± SD. Significance was analyzed by non-paired t test. P values <0.05 were considered statistically significant (*P < 0.05, **P < 0.01, ***P < 0.001)