Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Binding affinities of different histone peptides to the ePHD6 of MLL3 and MLL4 measured by ITC
| Histone peptides | Kd (μM) | |
|---|---|---|
| MLL3_(ePHD6)1055–1144 | MLL4_(ePHD6)1475–1564 | |
| H41–24 | 23 ± 3 | 13 ± 1 |
| H41–12 | NB | NB |
| H41–12R3me2a | NB | NB |
| H411–21 | 35 ± 2 | 52 ± 2 |
| H41–24R3A | 66 ± 3 | 28 ± 1 |
| H31–20 | NB | NB |
| H31–15K4me2 | NB | NB |
| H31–15K4me3 | NB | NB |
Kd values were calculated from single measurement and errors were estimated from fitting curve by Origin software package
NB, no detectable binding
