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. Author manuscript; available in PMC: 2019 Jan 4.
Published in final edited form as: Prog Mol Biol Transl Sci. 2018 Mar 30;157:21–40. doi: 10.1016/bs.pmbts.2017.11.022

Figure 2.1:

Figure 2.1:

(Top) Conventional ChIP-Seq and RNA-seq tracks on the linear genome demonstrate enhancer and promoter features. (Bottom) However, these traditional approaches miss the fact that the two elements, although quite distal in the linear genome, are actually in close physical proximity through looping interactions.