Table 1.

Characteristics of the Studies Included in the Meta-analysis

First Author	Country	Ethnicity	Case	Control	Cases					Control					HWE
					Genotypes			Alleles		Genotypes			Alleles
					DD	ID	II	D	I	DD	ID	II	D	I
Koh 2003	Singapore	Asian	182	643	23	80	79	126	238	56	305	282	417	869	0.036
Haiman 2003a		African Americans	257	631	77	118	62	272	242	221	310	100	752	510	0.614
Haiman 2003b	Japan	Asian	284	357	37	128	119	202	366	43	160	154	246	460	0.884
Haiman 2003c		Mixed	249	652	49	127	73	225	273	162	301	189	463	679	0.055
Haiman 2003d		Caucasians	292	402	84	129	79	297	287	124	187	91	435	369	0.204
Ladd 2005	Netherlands	Caucasians	114	4203	37	55	22	129	99	1133	2192	878	4458	3948	0.002
Yaren 2006	Turkey	Caucasians	44	46	25	17	2	67	21	28	12	6	68	24	0.028
Yaren 2007	Turkey	Caucasians	57	52	31	24	2	85	28	33	12	7	78	26	0.005
Van der 2008	Netherlands	Caucasians	153	655	54	67	32	175	131	185	329	141	699	470	0.815
Alves Corrêa 2009	Brazil	Mixed	101	307	61	20	20	142	60	141	113	53	395	219	≤0.001
Namazi 2010	Iran	Asian	70	70	20	42	8	82	58	29	34	7	92	48	0.514
Siddiqi 2010	India	Asian	130	228	62	43	25	167	93	96	107	25	299	157	0.552
Mendizábal-Ruiz 2011	Mexico	Mixed	63	288	53	6	4	112	14	63	151	74	277	299	0.394
Felipe 2011	Colombia	Mixed	50	50	10	23	17	43	57	10	24	16	44	56	0.854
Fishchuk 2013	Ukraine	Caucasians	131	102	41	53	37	135	127	21	50	31	92	112	0.918
Xiaomei 2014	China	Asian	123	72	61	32	30	154	92	36	19	17	91	53	≤0.001
El-Sharkawy 2014	Egypt	African	70	50	29	28	13	86	54	21	21	8	63	37	0.483
Ghosh 2015	India	Asian	108	128	62	28	18	152	64	32	50	46	114	142	0.017
Kumar 2016	India	Asian	213	213	35	86	92	156	270	24	77	112	125	301	0.061
Singh 2018	India	Asian	155	150	86	59	10	231	79	29	74	47	132	168	0.989

HWE, Hardy Weinberg Equilibrium