eTable 1. Results of the per-protocol analyses.

Endpoints	Adj. marginal means, IG [95% confidence interval]	Adj. marginal means, CG [95% confidence interval]	P-value
PHQ-9 remission (<5)	0.241 [0.155; 0.326]	0.111 [0.048; 0.174]	0.023*
PHQ-9 response (50% reduction)	0.225 [0.131; 0.319]	0.108 [0.036; 0.180]	0.059
PHQ-9 dimensional	8.109 [7.25; 8.97]	9.282 [8.71; 7.25]	0.026*
GAD7	6.722 [5.94; 7.50]	6.939 [6.33; 7.55]	0.670
Depression-related behavior	3.020 [2.79; 3.25]	2.986 [2.81; 3.17]	0.820
RS–13	59.204 [56.89; 61.51]	59.622 [57.43; 61.81]	0.798
PSS	16.163 [15.71; 16.62]	15.635 [15.15; 16.12]	0.120
EQ-5D Index	0.61 [0.57; 0.65]	0.56 [0.51; 0.60]	0.102

Analyses based on n = 210; * significant difference between the intervention group and the control group

Adj., adjusted; IG, intervention group; CG, control group; PHQ, Patient Health Questionnaire; GAD-7, Generalized Anxiety Disorder Scale;

RS-13, Resilience Scale (short form); PSS, problem-solving skills; EQ-5D-3L, questionnaire on health-related quality of life