Table 1.
Summary of results of elastic modulus versus proliferation assays under no drugs, defactinib, and EGFR inhibition. Statistical significance: * p < 0.05 when S1 and S3 values were compared; & p < 0.05 when values of S2 and S3 were compared.
| Stiffness Sensitivity Summary | |||
|---|---|---|---|
| Cell Line | Proliferation Rate Highest in Normal Condition | Proliferation Rate Highest in Defactinib | Proliferation Rate Highest in EGFR Inhibition |
| U373-MG | S3 *,& | S1 * | No distinct preference |
| A172 | S2 & and S3 * (DAY 4) | S1 * | S1 * and S2 & |
| U87-MG | S2 & | S2 | No distinct preference |
| U87-EGFRvIII | S3 | S1 | S1 |