Figure 2.

Characterization of bNAb-Modified HSPCs

(A) GFP expression in human fetal liver CD34⁺ cells, analyzed 1 day post-transduction. (B) CD34⁺ colony assays. The percentages of erythroid (BFU-E), granulocyte-macrophage (GM, G, and M), and multipotent granulocyte, erythroid, macrophage, and megakaryocyte (GEMM) progenitor colonies are indicated. Total number of colonies per condition is indicated above the histograms, and percentage of lentivirus (LV)-positive colonies, quantified by PCR, is indicated below. (C) Representative images of colony morphology and GFP expression for each group. Scale bar, 1 mm.