Table 3.
Univariate regression analysis of CNV area (mm2) and vessel density
| Variables | CNV area (mm2)
|
CNV vessel density
|
||||
|---|---|---|---|---|---|---|
| β coefficient | 95% CI | P-value | β coefficient | 95% CI | P-value | |
|
| ||||||
| Age | 0.09 | 0.03 to 0.15 | 0.004 | −0.002 | −0.01 to 0.002 | 0.30 |
| Gender | 0.43 | −1.7 to 2.5 | 0.67 | 0.01 | −0.09 to 0.11 | 0.84 |
| Eye (OD vs OS) | −0.38 | −2.3 to 1.5 | 0.67 | 0.06 | −0.03 to 0.15 | 0.15 |
| OCT-A platform (Zeiss vs Optovue) | −1.82 | −3.9 to 0.2 | 0.08 | 0.10 | 0.004 to 0.20 | 0.04 |
| Number of prior injections | 0.09 | 0.01 to 0.16 | 0.03 | −0.002 | −0.01 to 0.002 | 0.29 |
| Months since last injection | −0.03 | −0.08 to 0.03 | 0.34 | 0.001 | −0.001 to 0.004 | 0.36 |
| LogMAR VA | 0.92 | −3.5 to 5.3 | 0.66 | 0.03 | −0.19 to 0.24 | 0.81 |
| Presence of subretinal fluid | 0.24 | −1.8 to 2.3 | 0.80 | −0.0002 | −0.1 to 0.1 | 0.99 |
| Prior PDT | 0.46 | −1.8 to 2.7 | 0.67 | −0.10 | −0.20 to −0.01 | 0.04 |
| CNV type (1 vs 2) | −1.60 | −3.3 to 0.12 | 0.07 | −0.05 | −0.14 to 0.05 | 0.31 |
| Diagnosis (AMD vs WDS) | −2.22 | 0.6 to 3.8 | 0.01 | 0.02 | −0.12 to 0.08 | 0.71 |
Note: 95% CIs and P-values are for the β coefficient.
Abbreviations: AMD, age-related macular degeneration; CNV, choroidal neovascularization; logMAR VA, logarithm of the minimal angle of resolution visual acuity; OCT-A, optical coherence tomography angiography; PDT, photodynamic therapy; WDS, white dot syndromes.