Table 2.
Clinical characteristics of the study population by tertiles of hs-cTnT
| Tertile 1 (low), ≤0.009 ng/mL (n=253) | Tertile 2 (middle), 0.009–0.020 ng/L (n=231) | Tertile 3 (high), ≥0.020 ng/L (n=231) | P-value | |
|---|---|---|---|---|
| Baseline | ||||
| Age, years | 79.68±6.11 | 83.04±5.24 | 84.77±5.37 | <0.001 |
| Male sex, % | 138 (54.6) | 152 (65.8) | 180 (77.9) | <0.001 |
| Body-mass index, kg/m2 | 23.36±3.30 | 23.62±3.30 | 23.77±3.27 | 0.38 |
| Heart rate, beats/min | 72.28±12.10 | 74.23±13.21 | 75.23±13.51 | 0.056 |
| Systolic pressure, mmHg | 131.44±16.02 | 129.82±16.78 | 130.99±15.81 | 0.53 |
| Diastolic pressure, mmHg | 70.33±8.58 | 71.15±9.17 | 69.87±9.21 | 0.34 |
| Active smoking | 21 (8.3) | 18 (7.8) | 18 (7.8) | 0.97 |
| Comorbidities | ||||
| SCAD, n (%) | 64 (25.3) | 78 (33.8) | 91 (39.4) | 0.004 |
| Hypertension, n (%) | 190 (75.1) | 182 (78.8) | 200 (86.6) | 0.006 |
| DM, n (%) | 76 (30.0) | 97 (42.0) | 99 (42.9) | 0.005 |
| Cerebral infarction, n (%) | 144 (56.9) | 136 (58.9) | 152 (65.8) | 0.11 |
| COPD, n (%) | 37 (14.6) | 42 (18.2) | 59 (25.5) | 0.009 |
| CKD, n (%) | 43 (17.0) | 49 (21.2) | 84 (36.4) | <0.001 |
| AF, n (%) | 30 (11.9) | 45 (19.5) | 31 (13.4) | 0.052 |
| Biochemistry | ||||
| TC, mmol/L | 4.21±0.91 | 4.09±0.96 | 3.88±0.96 | <0.001 |
| TG, mmol/L | 1.13 (0.83–1.56) | 1.00 (0.78–1.38) | 0.98 (0.74–1.35) | 0.004 |
| HDL-C, mmol/L | 1.30±0.38 | 1.23±0.41 | 1.22±0.39 | 0.028 |
| LDL-C, mmol/L | 2.50±0.76 | 2.45±0.78 | 2.26±0.80 | 0.003 |
| Hb, g/L | 131.34±16.64 | 128.84±19.39 | 123.52±22.00 | <0.001 |
| ALT, mmol/L | 14.75 (11.45–18.55) | 14.10 (10.20–18.70) | 14.40 (10.60–21.40) | 0.54 |
| eGFR | 78.45±22.69 | 76.48±23.59 | 67.58±27.22 | <0.001 |
| Echocardiography | ||||
| LVEF, % | 59.92±3.35 | 59.33±3.95 | 57.90±5.35 | <0.001 |
| LVMI, g/m2 | 121.15±24.46 | 127.98±27.95 | 132.95±29.81 | <0.001 |
Abbreviations: AF, atrial fibrillation; CKD, chronic kidney disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; HDL-C, high-density-lipoprotein cholesterol; hs-cTnT, high-sensitivity cardiac troponin T; LDL-C, low-density-lipoprotein cholesterol; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; SCAD, stable coronary artery disease; TC, total cholesterol; TG, triglycerides.