Table 4.
High LA (18% Fat) | High LA (36% Fat) | Low LA (18% Fat) | Low LA (36% Fat) | |
---|---|---|---|---|
Bodyweight (g) | 376.4 ± 4.65 | 384.41 ± 11.00 | 384.34 ± 16.90 | 353.63 ± 9.55 |
Heart (% BW) | 0.25 ± 0.01a | 0.26 ± 0.01a | 0.28 ± 0.02b | 0.28 ± 0.01b |
Lungs (% BW) | 0.37 ± 0.05 | 0.36 ± 0.03 | 0.38 ± 0.05 | 0.36 ± 0.04 |
Kidney (%BW) | 0.53 ± 0.02 | 0.50 ± 0.01 | 0.53 ± 0.02 | 0.54 ± 0.02 |
Liver (% BW) | 4.01 ± 0.14 | 3.95 ± 0.07 | 4.10 ± 0.10 | 3.94 ± 0.10 |
Brain (% BW) | 0.47 ± 0.02 | 0.46 ± 0.01 | 0.50 ± 0.03 | 0.53 ± 0.02 |
Gonadal Fat (% BW) | 2.95 ± 0.03 | 2.38 ± 0.18 | 2.33 ± 0.18 | 3.04 ± 0.58 |
Retroperitoneal Fat (% BW) | 1.18 ± 0.17 | 1.18 ± 0.17 | 1.18 ± 0.011 | 1.79 ± 0.24 |
Liver mRNA Expression | ||||
Fasn | 5.51 ± 1.33 | 2.83 ± 0.59 | 6.08 ± 2.31 | 4.24 ± 1.21 |
Lpl | 3.13 ± 1.00 | 2.39 ± 0.75 | 2.52 ± 0.80 | 1.74 ± 0.71 |
Pparg | 5.81 ± 1.85 | 2.30 ± 0.77 | 3.38 ± 0.78 | 2.09 ± 0.73 |
Srebf1 | 1.33 ± 0.31 | 1.20 ± 0.22 | 1.23 ± 0.50 | 2.67 ± 1.14 |
Retroperitoneal Fat mRNA Expression | ||||
Fasn | 0.12 ± 0.05 | 0.07 ± 0.04 | 0.15 ± 0.05 | 0.13 ± 0.07 |
Lpl | 2.18 ± 0.66 | 1.82 ± 0.81 | 2.18 ± 0.72 | 1.48 ± 0.16 |
Pparg | 1.15 ± 0.47 | 1.40 ± 0.59 | 1.76 ± 0.48 | 1.03 ± 0.17 |
Srebf1 | 1.17 ± 0.40 | 1.16 ± 0.41 | 1.38 ± 0.42 | 1.11 ± 0.13 |
Lep | 2.59 ± 0.67 | 2.73 ± 0.99 | 2.31 ± 0.69 | 1.83 ± 0.34 |
Data are presented as mean values ± SEM (n = 4–6 per group). LA linoleic acid, BW bodyweight, mRNA messenger ribonucleic acid, Fasn fatty acid synthase, Lpl lipoprotein lipase, Pparg peroxisome proliferator-activated receptor gamma, Srebf1 sterol regulatory element-binding protein 1, Lep leptin. Mean values with unlike superscript letters were significantly different (P < 0.05)