Fig. 5.

Partial correlation matrix of sPTB-associated CpG sites in Cord Blood and Placenta. Partial correlation matrix between DNA methylation (DNAm) level of combined 32 CpG sites in cord blood and DNAm of those CpG sites in placenta, controlling for status of sPTB, maternal age, maternal education level, maternal pre-pregnancy BMI and newborns’ gender. The x axis represents the CpG sites in placenta. The y axis represents the CpG sites in cord blood. The dashed line highlights the correlation between DNAm of CpG sites in one tissue with the same particular CpG site in the other tissue. * p-value < 0.05, ** p-value < 0.001