Table 3.
Sputum cell numbers by asthma inflammatory phenotypes
EA | NEA | p value | |
---|---|---|---|
n | 8 | 7 | |
Total cell count (106/mL) | 5.4 (1.5, 10.1) | 4.1 (3.7, 11.8) | 0.965 |
Viability (%) | 87.8 (64.6, 95.8) | 70.5 (57.2, 94.3) | 0.699 |
Neutrophils (%) | 29.8 (23.8, 61.4) | 50.3 (9.0, 55.0) | 0.980 |
Neutrophils (104/mL) | 150.8 (38.5, 591.6) | 211.8 (103.8, 700.9) | 0.699 |
Eosinophils (%) | 6.6 (6.1, 8.8) | 1.0 (0.0, 1.5) | < 0.001 |
Eosinophils (104/mL) | 45.3 (9.1, 106.5) | 4.6 (0.8, 6.9) | 0.009 |
Macrophages (%) | 39.1 (27.8, 63.4) | 44.5 (35.0, 73.5) | 0.536 |
Macrophages (104/mL) | 238.0 (94.0, 314.7) | 251.4 (159.3, 459.8) | 0.589 |
Lymphocytes (%) | 5.1 (0.4, 6.4) | 1.8 (1.0, 3.0) | 0.381 |
Lymphocytes (104/mL) | 4.6 (1.2, 35.4) | 9.4 (4.4, 20.2) | 0.833 |
Columnar epithelial cells (%) | 0.8 (0.1, 6.6) | 2.8 (1.3, 10.0) | 0.141 |
Columnar epithelial cells (104/mL) | 1.9 (0.0, 7.1) | 14.0 (9.1, 28.9) | 0.026 |
Squamous cells (%) | 3.0 (0.7, 15.8) | 6.3 (3.8, 19.5) | 0.161 |
Data is reported as median (q1, q3). Data was analysed by the Mann-Whitney U test