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. 2019 Jan 3;20:2. doi: 10.1186/s12931-018-0963-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Treatment with NEt-4IB attenuates PPE-induced airway inflammation. a Experimental protocol. b Cell composition in BAL fluid. c (a) KC, (b) CXCL5 (c) IL-6, (d) IL-1β in BAL fluid, and (e) perforin, (f) IFN-γ, (g) IL-17, and (h) TNF-α in the lungs. The results for each group are expressed as the means ± SEM. This experiment was started with 10 mice in each group, and no mice were died during the experimental period. * Significant differences (P < 0.05) between PBS/vehicle and PPE/vehicle. # Significant differences (P < 0.05) between PPE/vehicle and PPE/NEt-4IB 0.015%